Frequently asked questions
About Wartner 2nd generation
What components make up the Wartner 2nd Generation 2nd Generation treatment?
Wartner 2nd Generation Wart Remover contains an aerosol can with a mixture of dimethyl ether and propane, an applicator holder and foam applicators; it contains a file to remove calloused skin on top of the verruca prior to the treatment.
How does Wartner 2nd Generation work?
Wartner 2nd Generation works in a similar way to the liquid nitrogen freezing method used by GPs. The freezing agent is applied to the foam applicator; you then freeze the wart or verruca by applying the saturated foam applicator for a few seconds. As a result of this freezing, the growth should fall off after about 10-14 days. Wartner 2nd Generation is not harmful to the environment.
Will using Wartner 2nd Generation hurt?
Freezing the skin may lead to a slight aching, stinging sensation that may cause some discomfort. This will pass quickly, leaving a small blister under the treated area.
Is Wartner 2nd Generation safe to use?
Yes, Wartner 2nd Generation is safe to use if you follow the instructions carefully; however we do not advise use on children under the age of four.
CE Marked and classified as a Class II A Medical Device, which conforms to European guidelines (Council Directive 93/42/EEC) Wartner 2nd Generation has been assessed by several scientific and medical experts as being a safe method for the removal of warts and verrucas: "Wartner 2nd Generation meets all lawful requirements which serve to guarantee consumer safety". Mr J Sleumer - Laboratory Manager Eurofill - Zaandam, The Netherlands
Dermatologists confirm Wartner 2nd Generation's safety: "The effectiveness of Wartner 2nd Generation is comparable to that of the classic technique (Liquid Nitrogen = doctor's method) in every respect, and the freezing effect it has is similar to that obtained by Liquid Nitrogen, perhaps a little slower (20" application instead of 3" application), which I think is safer and less painfull" Dr J M Gray - Dermatologist - Paris, France
"The expert opinion is that Wartner 2nd Generation freezing liquid can be applied by patients themselves, and therefore sold to the public freely" Dr I H Boersma - Dermatologist - Albert Schweizer Hospital - Zwijndrecht, The Netherlands
When should Wartner 2nd Generation not be used?
Wartner 2nd Generation may not be used for:
- removing warts on the face or the genitals;
- skin conditions with signs of inflammation;
- dark moles, dark-colored, hairy or otherwise unusual looking skin conditions which resemble warts;
- warts on children under the age of four.
What are the most important parameters for an effective treatment based on Cryotherapy?
- Temperature of the application
- Contact time on skin
Is the gas mixture (DMEP) used as effective as liquid nitrogen used by the doctor?
Wartner 2nd Generation is based on the liquid nitrogen method of cryotherapy, which is used by doctors. Clinical studies have proved that Wartner 2nd Generation is as effective as liquid nitrogen.
A clinical study to compare efficacy, tolerance and safety of 2 types of cryotherapy (liquid nitrogen (LN) and dimethylether/propane (DMEP) was performed by family physicians for warts on 124 patients (174 warts). Design of the study: randomized, multi-centered, controlled clinical trial with single blind assessment. Conclusions: The results show that both cryogenic agents were >90% effective. Liquid Nitrogen has a temperature of -196ºC, whilst DMEP is -57ºC and therefore much less likely to cause deep tissue damage.
Dermatologists confirm Wartner 2nd Generation's effectiveness: "the efficacy of Wartner 2nd Generation freezing fluid is as effective as commonly used liquid nitrogen (= doctor's method). In case of thick callosity we remove the callosity by scraping in a gentle way and apply Wartner 2nd Generation freezing liquid effectively" Dr I H Boersma - Dermatologist - Albert Schweizer Hospital - Zwijndrecht, The Netherlands.
"The effectiveness of Wartner 2nd Generation is comparable to that of the classic technique (Liquid Nitrogen = doctor's method) in every respect, and the freezing effect it has is similar to that obtained by Liquid Nitrogen, perhaps a little slower (20" application instead of 3" application), which I think is safer and less painful" Dr J M Gray - Dermatologist - Paris, France
What temperature reaches Wartner 2nd Generation?
Wartner 2nd Generation reaches a temperature on skin of -50° which is the coldest therapeutic temperature reached on the market as a cryotherapy.

How does it compare to other cryo products in the market?
Based on clinical research, Wartner clearly outperforms competition in relation to therpautic temperature and saturation of the applicator.
Will I get a scar from using Wartner 2nd Generation?
If you follow all the directions in the instruction leaflet correctly, using Wartner 2nd Generation will not result in scarring. Skin discoloration may occasionally occur, but will disappear over time.
If I have more than one common wart or verruca, can I treat them all at once?
No, if you have several common warts or verrucas in the same area, treat only one at a time. Treat each remaining wart or verruca separately with a 2-week interval between treatments.
Is Wartner 2nd Generation difficult to apply?
No. Wartner 2nd Generation should be applied with precision, but it's not difficult. The information leaflet explains exactly how you should apply Wartner 2nd Generation.
How long should I press on the valve?
You press the valve down firmly for three seconds.
Should I press the cold foam applicator onto the wart or verruca immediately?
No. After pressing the foam applicator into the valve for 3 seconds, 20 seconds need to be waited before application on skin. This waiting period allows the gas on the foam applicator to reduce even further in temperature, resulting in the most effective therapeutic temperature for a fast and convenient removal of the wart/verruca.
How long can I apply the cold foam applicator to a wart or verruca for?
Warts: (max.) 20 sec.
Verrucas: (max.) 40 sec.
How often may I use the foam applicator?
Each foam applicator may be used once only and should then be discarded to avoid spreading the virus.
How many warts or verrucas may I treat per hand or foot simultaneously?
Only one per hand or foot may be treated by Wartner 2nd Generation at a time.
How often may I use Wartner 2nd Generation?
Wartner 2nd Generation may be used up to 3 times per wart or verruca. You should leave a 2-week interval between treatments.
I’ve tried Wartner 2nd Generation once, but nothing happened, what do I do next?
For old or persistent warts or verrucas, two or three applications maybe required. To help with treatment, remove the top layer of skin with a pumice stone or emery board; this will expose the core. Treat each wart or verruca with a 2-week interval between treatments. Consult your doctor if there is no improvement after three treatments.
Will successfully treated common warts or verrucas return?
A successfully treated wart or verruca usually means that it has been removed permanently. The body's immune system will normally purge any remaining traces.
When should I not use Wartner 2nd Generation?
- If you are diabetic.
- If you are pregnant.
- If the common wart or verruca is located in a sensitive area with thin skin (e.g. the face, neck, armpits, chin, breast) or on genital warts.
- If the nearby or affected skin is inflamed.
- If you are not certain that the skin condition you are treating is a common wart or verruca.
- Wartner 2nd Generation should not be used on children under the age of four.
Are there any side-effects from using Wartner 2nd Generation?
There are a number of possible side-effects:
- As with all freezing methods, the skin may turn white temporarily.
- A blister develops under the wart, but this is part of the treatment and is harmless.
- Using Wartner 2nd Generation may cause some discomfort.
- Applying the foam applicator to the wart or verruca for too long may lead to local tissue death. You should therefore follow the instructions carefully and apply the treatment for the time specified based on the size of the wart or verruca.
- Always use Wartner 2nd Generation very carefully and accurately. If you're not careful, scars and nerve damage may occur.
How serious are the various side-effects?
- White coloration of the skin: as soon as you press the foam applicator onto the problem area, the skin turns white. This discoloration quickly decreases as soon as the foam applicator is removed.
- The appearance of a blister: this blister will disappear as soon as the wart or verruca falls off the skin. New skin will already have formed under the blister.
- Discomfort during use: a stinging sensation may occur when the foam applicator is pressed onto the skin. This stinging sensation quickly fades once the foam applicator is removed.
- Local tissue death: this will only occur during deep freezing of the skin. Therefore, never hold the foam applicator on a wart for more than 20 seconds (40 seconds for verrucas)
- Scars and nerve damage: this will only occur from careless use caused by not following the instructions on the information leaflet. Never hold the foam applicator on the wart for more than 20 seconds (40 seconds for verrucas) to ensure that there is no deep freezing and therefore no damage.
What should I do if the side-effects do not disappear?
Always consult a doctor if the stinging sensation does not disappear or if other complications occur through using Wartner 2nd Generation.
Who can use Wartner 2nd Generation 2nd Generation?
Wartner 2nd Generation may be used by most adults. You can also use Wartner 2nd Generation to remove warts and verrucas on children over the age of four, but the treatment must be carried out by an adult.
Can Wartner 2nd Generation be used to treat children?
Yes, Wartner 2nd Generation is suitable for children over the age of four.
Is it dangerous to use Wartner 2nd Generation to treat children under four?
We do not recommend the use of Wartner 2nd Generation to treat children under the age of four.
Can Wartner 2nd Generation be used by pregnant women?
No. Do not use Wartner 2nd Generation if you are pregnant or breastfeeding.
How quickly will the wart or verruca disappear?
It takes approximately 10-14 days for the wart or verruca to disappear.
What should I do if the wart doesn’t disappear after 14 days?
If the wart or verruca doesn't disappear after 14 days, you can treat it again. You can treat each wart or verruca with Wartner 2nd Generation a maximum of three times, with a 2-week interval between each treatment.
What should I do if it doesn’t disappear after three treatments with Wartner 2nd Generation?
If the wart or verruca doesn't disappear after three treatments, you should go to your doctor.
Why should I use Wartner 2nd Generation if I can also go to the doctor for the same wart treatment?
Wartner 2nd Generation has a number of important advantages. It saves time and is easy to use. You no longer have to wait at the doctor's surgery. The liquid nitrogen that your doctor uses has a much lower temperature than Wartner 2nd Generation. Because of this Wartner 2nd Generation is less painful but just as effective.
What is the difference between the liquid nitrogen method at the doctor’s surgery and a treatment with Wartner 2nd Generation?
The liquid nitrogen that your doctor uses has a much lower temperature than Wartner 2nd Generation. Because of this Wartner 2nd Generation is less painful but just as effective.
What is the best way to take care of the area I’ve treated?
Make sure that the area stays clean. Do not pick at or scratch it. Protect blisters with an adhesive plaster and do not puncture them.
Can I let the area I’ve treated get wet?
Yes. You can shower and swim after treatment with Wartner 2nd Generation.
Is Wartner 2nd Generation harmful to the environment?
No. Wartner 2nd Generation doesn't harm the environment.
Who makes Wartner 2nd Generation?
Wartner 2nd Generation is manufactured by Omega Teknika - Farnham Drive, Finglas, Dublin 11, Ireland, and is distributed by Omega Pharma by its local affiliates.
Where can I buy Wartner 2nd Generation?
You can buy Wartner 2nd Generation at your local pharmacy or supermarket.
How to apply Wartner 2nd Generation?
STEP 1
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Hold the blue end of the foam applicator between the thumb and index finger and squeeze until a small opening appears. Slide the opening of the foam applicator onto the stick of the applicator holder until the stick is no longer visible. |
STEP 2
STEP 3
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After saturation of the foam applicator, wait for 20 sec before topical application in order to further reduce application temperature and thus ensuring a better efficacy of Wartner. |
STEP 4
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After the 20 seconds waiting time, push the applicator holder with the foam applicator lightly on the wart.
Ensure constant contact with the area to be treated. The foam applicator should be applied to the area for the required treatment time. A slight aching, stinging sensation will occur as a result of freezing. After treating the wart, wait 2 minutes before using a tissue to remove the foam applicator from the holder. Discard the foam applicator after single use. Do not reuse the foam applicator or touch the tip of the foam applicator with bare hands to ensure that you don’t re-infect the skin with the wart virus. |
2 ADDITIONAL STEPS FOR VERRUCAS for optimal preparation and after treatment
PRIOR TO THE TREATMENT
First, soak the foot in warm water for 5 minutes and afterwards rub the callous with the file to expose the verruca.
STEP 1-4
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See above. Same as for the removal of warts |
STEP 5







